Stem Cells Research Today is a free monthly online journal that collates and summarizes the latest research about Stem Cells, including details on research, transplants, therapy, benefits.

Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells.

Turnpenny L, Spalluto CM, Perrett RM, O'shea M, Hanley KP, Cameron IT, Wilson DI, Hanley NA

M.R.C.P., and Lee Turnpenny, Ph.D., Human Genetics Division, University of Southampton, Duthie Building (M.P. 808), Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom. N.A.Hanley@soton.ac.uk.

The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations.

Published 2 March 2006 in Stem Cells, 24(2): 212-20.
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